Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus

A new antibacterial 3-monoacyl- -glycerol, nostochopcerol ( ), was isolated from a cultured algal mass of the edible cyanobacterium MAC0804NAN. The structure of compound was established by the analysis of NMR and MS data while its chirality was established by comparison of optical rotation values wi...

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Published inBeilstein journal of organic chemistry Vol. 19; no. 1; pp. 133 - 138
Main Authors Oku, Naoya, Hayashi, Saki, Yamaguchi, Yuji, Takenaka, Hiroyuki, Igarashi, Yasuhiro
Format Journal Article
LanguageEnglish
Published Germany Beilstein-Institut zur Föerderung der Chemischen Wissenschaften 2023
Beilstein-Institut
Subjects
Algae
antibacterial
Antimicrobial agents
Bacteria
Carbon
Chemistry
Chirality
Chromatography
Cyanobacteria
cyanobacterium
edible
Fatty acids
Glycerol
Gram-positive bacteria
Letter
Metabolites
monoacylglycerol
Nostochopsis lobatus
Ulcers
Thailand
India
monoacylglycerol
antibacterial
edible
Nostochopsis lobatus
cyanobacterium
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Summary:A new antibacterial 3-monoacyl- -glycerol, nostochopcerol ( ), was isolated from a cultured algal mass of the edible cyanobacterium MAC0804NAN. The structure of compound was established by the analysis of NMR and MS data while its chirality was established by comparison of optical rotation values with synthetically prepared authentics. Compound inhibited the growth of and at MIC of 50 μg/mL and 100 μg/mL, respectively.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1860-5397
2195-951X
1860-5397
DOI:10.3762/bjoc.19.13