Functionalization of cotton cellulose for improved wound healing

Wound dressing research has been determined by population aging, persistence of wound infection and the increase in chronic wound cases. Thus, besides mechanical protection, wound dressings must interact with the wound and improve the healing process. To achieve this demanding goal, wound dressing r...

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Published inJournal of materials chemistry. B, Materials for biology and medicine Vol. 6; no. 13; pp. 1887 - 1898
Main Authors Pinho, E, Soares, G
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 07.04.2018
Subjects
Aging
Cellulose
cellulosic materials
Chronic infection
Composite materials
Cotton
Drug delivery
Drug delivery systems
drugs
engineering
fabrics
Hydrogels
Maceration
Medical dressings
Pain
polymers
tissue repair
Wound healing
Wound infection
wound treatment
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ISSN2050-750X
2050-7518
2050-7518
DOI10.1039/c8tb00052b

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Summary:Wound dressing research has been determined by population aging, persistence of wound infection and the increase in chronic wound cases. Thus, besides mechanical protection, wound dressings must interact with the wound and improve the healing process. To achieve this demanding goal, wound dressing research has been focussing on the development of composite wound dressings that combine the best of two or more polymeric materials. Cellulosic materials are still the most used for wound management. Their importance is reflected in the number of publications on this subject in the textile engineering field. Textile wound dressing can cause maceration to the wound and pain during removal. However, the limitations of cellulosic wound dressings can be overcome by functionalization with hydrogels, which will maintain the moisture environment and improve the drug delivery ability of cotton. Therefore, the present review summarizes the composite materials research on the functionalization of cotton cellulose with hydrogels, to be applied as a wound dressing, and the methods and techniques used to synthesize those composites. Cotton functionalization with hydrogels improve it application as wound dressing.
Bibliography:Eva Pinho obtained her PhD in July 2014 under the co-supervision of Professor Mariana Henriques from the Centre of Biological Engineering (University of Minho), Graça Soares from the Centre for Textile Science and Technology (University of Minho) and Martin Grootveld from the School of Pharmacy (De Montfort University). Her PhD research was focused on developing antimicrobial wound dressings, using environmentally friendly procedures and natural compounds. After 2.5 years as a research scientist in Success Gadget, Nanotecnologia e Novos Materiais, Lda., she joined 2C2T (Centre for Textile Science and Technology) and is currently working as a post-doc research associate. At present, her research is mostly focused on surface functionalization of textile fibers to improve their applicability as wound dressings.
Graça Soares is an Assistant Professor at the Department of Textile Engineering of Minho University. She is a researcher from the Centre for Textile Science and Technology. Her research interests lie in the area of textile chemistry, ranging from materials functionalization to dyeing and finishing processes. She has collaborated actively with researchers in several other disciplines of materials and life sciences, namely in the developing of biofunctional materials. She holds one patent derived from her collaborative research. She has published numerous papers in various international journals and conference proceedings.
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ISSN:2050-750X
2050-7518
2050-7518
DOI:10.1039/c8tb00052b