Isolation and structure determination of the biologically active sphingolipids from marine sponge Haliclona species

In a continuation to our study on the marine sponge Haliclona species we have isolated three new cytotoxic components of sphingolipids (1-3). Methanolysis of the sphingolipid 1a-d in methanol produces fatty acid methyl ester. GC/MS was used to determine the length. The structure of each isolated com...

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Bibliographic Details
Published inNatural product research Vol. 23; no. 1; pp. 44 - 50
Main Authors Ayyad, Seif-Eldin N., Bahaffi, Saleh Omar S., Hashish, Nadia E.
Format Journal Article
LanguageEnglish
Published England Taylor & Francis Group 10.01.2009
Subjects
Animals
C NMR
cytotoxicity
Gas Chromatography-Mass Spectrometry
GC-MS
Haliclona
Haliclona - chemistry
Haliclona sponge
Marine
Marine Biology
Mice
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Oceans and Seas
sphingolipids
Sphingolipids - chemistry
Sphingolipids - isolation & purification
Sphingolipids - pharmacology
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Summary:In a continuation to our study on the marine sponge Haliclona species we have isolated three new cytotoxic components of sphingolipids (1-3). Methanolysis of the sphingolipid 1a-d in methanol produces fatty acid methyl ester. GC/MS was used to determine the length. The structure of each isolated compound has been determined on the basis of spectroscopic data and chemical evidence.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:1478-6419
1478-6427
DOI:10.1080/14786410701768246