Phylogenomic relationships and molecular convergences to subterranean life in rodent family Spalacidae

Furthermore, these convergent genes were enriched in the functional categories of monocarboxylic acid biosynthetic process, carboxylic acid transport, vascular morphogenesis, and response to oxidative stress, which are closely associated with adaptations to the hypoxic-hypercapnic underground enviro...

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Bibliographic Details
Published inDōngwùxué yánjiū Vol. 42; no. 5; pp. 671 - 674
Format Journal Article
LanguageEnglish
Published Kunming Kunming Institute of Zoology, The Chinese Academy of Sciences 18.09.2021
Subjects
Adaptation
Amino acids
Bamboo
Bayesian analysis
Carboxylic acids
Convergence
Divergence
Evolution
Genes
Genomes
Hypoxia
Mammals
Morphogenesis
Oxidative stress
Phylogenetics
Phylogeny
Probability theory
Proteins
Rodents
Statistical inference
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Summary:Furthermore, these convergent genes were enriched in the functional categories of monocarboxylic acid biosynthetic process, carboxylic acid transport, vascular morphogenesis, and response to oxidative stress, which are closely associated with adaptations to the hypoxic-hypercapnic underground environment. For each orthologous protein-coding gene, both Bayesian inference (BI) and maximum-likelihood (ML) approaches were used to reconstruct the phylogenetic relationships among the hoary bamboo rat, plateau zokor, blind mole-rat, and mouse based on the best-fitting substitution model estimated by jModelTest2 (Darriba et al., 2012). [...]the ratio of the number of convergent sites to the number of divergent sites (95/146) between branches I and III was not significantly larger than that (70/107) between branches II and III (P=0.98; two-tailed x2 test). To explore the molecular basis of the subterranean lifestyle in spalacids from these convergent genes, we performed Gene Ontology (GO) functional enrichment analysis of the 95 convergent genes between branches I and III using all one-to-one orthologous protein-coding genes as the background.
ISSN:0254-5853
DOI:10.24272/j.issn.2095-8137.2021.240