Traditional Chinese Medicine Use in the Pathophysiological Processes of Migraine

Migraine is a highly prevalent neurological disorder and has been the second leading cause of disability worldwide for many years. The pathophysiology of migraines is complicated, and most available medications have unpleasant side effects. Therefore, it is essential to understand the mechanism of m...

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Published inWorld Journal of Traditional Chinese Medicine Vol. 11; no. 1; pp. 1 - 15
Main Authors Wu, Mei-Rong, Ou, Yi, Han, Rui, Li, Tian-Tian, Wei, Ming-Yan, Guo, Hong, Miao, Yao-Dong, Wang, Kai, Zhang, Han, Li, Lin
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer - Medknow 2025
Medknow Publications and Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Edition2
Subjects
Care and treatment
Drugs
Health aspects
Inflammation
mechanisms
Medicine, Chinese
Migraine
Nervous system diseases
neurogenic inflammation
pathophysiology
Physiological aspects
Review Article
traditional chinese medicine
trigeminovascular system
China
Canada
traditional Chinese medicine
Mechanisms
migraine
trigeminovascular system
pathophysiology
neurogenic inflammation
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Summary:Migraine is a highly prevalent neurological disorder and has been the second leading cause of disability worldwide for many years. The pathophysiology of migraines is complicated, and most available medications have unpleasant side effects. Therefore, it is essential to understand the mechanism of migraine to develop potential preventive and therapeutic agents. Studies have confirmed that traditional Chinese medicine (TCM) can alleviate migraine by reducing neuroinflammation, oxidative stress, and apoptosis and regulating neurotransmitters and vascular function. Starting from the pathophysiological process of migraine, this review summarizes the mechanisms by which TCM improves neurovascular function after migraine to provide clues and a reference for the clinical application of TCM in the prevention and treatment of migraine and guide further research and development of new drugs.
ISSN:2311-8571
2589-2894
DOI:10.4103/wjtcm.wjtcm_90_24