Clinical outcomes of magnesium-incorporated oxidised implants: a randomised double-blind clinical trial

• Published in: Clinical oral implants research Vol. 25; no. 5; pp. 616 - 621
• Main Authors: Pang, Kang-Mi, Lee, Jung-Woo, Lee, Jin-Yong, Lee, Jai-Bong, Kim, Soung-Min, Kim, Myung-Jin, Lee, Jong-Ho
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.05.2014
• Subjects: Adult; Alveolar Bone Loss - etiology; bone-implant interactions; clinical research; clinical trials; Dental Implantation, Endosseous - methods; Dental Implants; Dental Prosthesis Design; Double-Blind Method; Female; Humans; Magnesium - chemistry; Male; Microscopy, Electron, Scanning; Middle Aged; Oxidation-Reduction; Prospective Studies; surface chemistry; Surface Properties; Titanium - chemistry; Treatment Outcome; clinical trials; surface chemistry; clinical research; bone-implant interactions
• ISSN: 0905-7161; 1600-0501; 1600-0501
• DOI: 10.1111/clr.12091

Objectives This study evaluated implant stability and clinical outcomes obtained with magnesium‐incorporated oxidised implants (Mg titanate) and compared them to those blasted magnesium‐incorporated oxidised implants (blasted Mg titanate). Patients and methods Mg titanate was manufactured using the microarc oxidation (MAO) process. To obtain blasted Mg titanate, the MAO process was performed after blasting with TiO2 particles. The 15‐month, randomised, double ‐blind clinical trial was conducted on 54 implants in 40 patients (Mg titanate, 27 implants in 18 subjects; blasted Mg titanate, 27 implants in 22 subjects), in whom 4.0 mm × 10 mm implants were placed to restore the unilateral loss of one or two molars in the mandible. The final prosthesis was attached 3 months postoperatively. Implant stability was measured by the implant stability quotient (ISQ) and periotest value (PTV) at the time of implant insertion, and 2, 3, and 15 months postoperatively. Marginal bone loss was evaluated at 2, 6, and 15 months postoperatively. Soft tissue analysis was performed at 15 months postoperatively. Results Both implant systems showed high stability at all time points (>71). Mean marginal bone loss was 0.71 ± 0.65 mm and 0.75 ± 0.73 after 15 months in Mg titanate and blasted Mg titanate, respectively. There were no significant differences between the two implant surfaces with respect to ISQ(P = 0.988), PTV(P = 0.935), and marginal bone loss(P = 0.807) after 15 months. Conclusion The success rate after 1 year of follow‐up was 100% for both magnesium‐incorporated oxidised implants. There were no significant differences in the clinical outcomes between the two surfaces at 15 months follow‐up.