Applicability of a standardized thoracic endograft with a single branch for the left subclavian artery to treat aortic disease involving the distal arch

• Published in: Journal of vascular surgery Vol. 72; no. 5; pp. 1516 - 1523
• Main Authors: Mougin, Justine, Sobocinski, Jonathan, Kratzberg, Jarin, Fabre, Dominique, Haulon, Stéphan
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2020; Elsevier
• Series: Journal of Vascular Surgery
• Subjects: Aneurysm, Dissecting - surgery; Aorta, Thoracic - anatomy & histology; Aorta, Thoracic - diagnostic imaging; Aorta, Thoracic - surgery; Aortic Aneurysm, Thoracic - surgery; Blood Vessel Prosthesis Implantation - instrumentation; Computed Tomography Angiography; Endovascular Procedures - instrumentation; Feasibility Studies; Humans; Imaging, Three-Dimensional; Left subclavian artery; Life Sciences; Multicenter Studies as Topic; Observational Studies as Topic; OTS endograft; Preoperative Period; Prospective Studies; Retrospective Studies; Stents; Subclavian Artery - anatomy & histology; Subclavian Artery - diagnostic imaging; Subclavian Artery - surgery; TEVAR; Treatment Outcome; TEVAR; OTS endograft; Left subclavian artery
• ISSN: 0741-5214; 1097-6809
• DOI: 10.1016/j.jvs.2020.02.011

Coverage of the left subclavian artery (LSA) origin during thoracic endovascular aortic repair (TEVAR) is associated with increased neurologic complications. Our group is involved in the development of an off-the-shelf (OTS) thoracic endograft incorporating a left common carotid artery (LCCA) scallop and a retrograde inner branch for LSA perfusion. This study aimed to evaluate the arch morphology of patients treated by TEVAR and requiring LSA coverage to determine the applicability of this OTS device. The preoperative anatomy of consecutive patients from three separate cohorts treated with TEVAR with LSA coverage was studied. High-quality preoperative computed tomography angiography images were analyzed on an imaging workstation. Location of the origin of the supra-aortic trunks and their anatomic relationship were depicted in all patients; the LCCA origin was set as reference point. We determined the proportion of arch morphology in our cohort of patients eligible for this OTS device configuration. There were 196 patients included in this study, 132 in the dissection cohort and 64 in the aneurysm cohort. The median length from the lower margin of the LCCA to the proximal aspect of the pathologic process was 25.0 mm (18.2-35.2 mm), with 68.4% (n = 134) of our cohort presenting with a proximal sealing zone length >20 mm. The median LCCA-LSA distance was 20.8 mm (16.6-25.4 mm). The median clock position of the LSA from the LCCA was −10 minutes (−30 to 0 minutes). In total, 127 patients (64.8%) could have been treated with the current OTS branched TEVAR configuration; 59 were excluded for proximal neck length distal to the LCCA <20 mm and 10 because of the clock position of the LCCA, and 9 first required a vertebral artery transposition. The low variability of LSA and LCCA locations in patients with distal aortic arch disease offers wide applicability of a new standardized thoracic branched endograft.