Acute renal failure caused by Amanita oberwinklerana poisoning

Mushrooms of the sections Lepidella and Amidella in the genus Amanita can cause acute renal injury. The paper reports the first two known cases of acute renal failure after ingestion of A. oberwinklerana in China. The cases' clinical symptoms were characterized by gastrointestinal toxicity 6 h...

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Bibliographic Details
Published inMycoscience Vol. 58; no. 2; pp. 121 - 127
Main Authors Fu, Xiaoyun, Fu, Bao, He, Zhengmi, Gong, Minmin, Li, Zhigui, Chen, Zuohong
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.03.2017
The Mycological Society of Japan
Subjects
ITS sequence
Mushroom poisoning
Nephrotoxic syndrome
ITS sequence
Mushroom poisoning
Nephrotoxic syndrome
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Summary:Mushrooms of the sections Lepidella and Amidella in the genus Amanita can cause acute renal injury. The paper reports the first two known cases of acute renal failure after ingestion of A. oberwinklerana in China. The cases' clinical symptoms were characterized by gastrointestinal toxicity 6 h after ingestion followed by mild hepatitis and severe acute renal failure, which are identical to the clinical symptoms of Amanita nephrotoxic syndrome. The mushroom species was identified using morphological and internal transcribed spacer (ITS) sequence data. HPLC analyses detected no amatoxins or phallotoxins in this species. The clinical syndromes and toxin profiles, as well as the phylogenetic analysis based on ITS sequences, strongly support the transfer of A. oberwinklerana from the section Phalloideae to the section Lepidella. •Acute renal failure caused by Amanita oberwinklerana was reported for the first time.•The species was identified based on both morphological and ITS sequence data.•Both clinical and biochemical evidences supported its allocation to sect. Lepidella.
ISSN:1340-3540
1618-2545
DOI:10.1016/j.myc.2016.12.004