Symmetrical Drug-Related Intertriginous and Flexural Exanthema: Two Cases and Brief Literature Review

It has been reported that there are a range of causative drugs related to symmetrical drug-related intertriginous and flexural exanthema (SDRIFE). The causative drugs reported so far include the following: antibiotics, intravenous immunoglobulin, chemotherapeutic agents, and biologics. In this study...

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Published inAnnals of dermatology Vol. 30; no. 5; pp. 606 - 609
Main Authors Seok, Joon, Kim, Jae Min, Park, Kui Young, Seo, Seong Jun
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Dermatological Association; The Korean Society for Investigative Dermatology 01.10.2018
대한피부과학회
Subjects
Case Report
피부과학
Chinese herbal ball
Mosapride
Symmetrical drug-related intertriginous and flexural exanthema
Ranitidine
Urushiol
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Summary:It has been reported that there are a range of causative drugs related to symmetrical drug-related intertriginous and flexural exanthema (SDRIFE). The causative drugs reported so far include the following: antibiotics, intravenous immunoglobulin, chemotherapeutic agents, and biologics. In this study, we report two cases of SDRIFE and a review of the previous literature. We believe that our study makes a significant contribution to the literature because it demonstrates that intradermal injection of the Chinese herbal ball, and not its topical application, elicited a reaction that predicted the occurrence of SDRIFE. This finding is important for the diagnosis of SDRIFE in future studies. Our findings also provide evidence for a SDRIFE reaction after exposure to ranitidine and mosapride.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:1013-9087
2005-3894
2005-3894
DOI:10.5021/ad.2018.30.5.606