Effect of concentric exercise on serum muscle and collagen markers

The effect of an acute bout of high-intensity concentric exercise on serum muscle and collagen marker proteins was studied in nine male students. The muscle-derived serum carbonic anhydrase III, myoglobin, and creatine kinase all increased as a result of the exercise. Serum type I procollagen carbox...

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Bibliographic Details
Published inJournal of applied physiology (1985) Vol. 75; no. 3; p. 1272
Main Authors Virtanen, P, Viitasalo, J T, Vuori, J, Väänänen, K, Takala, T E
Format Journal Article
LanguageEnglish
Published United States 01.09.1993
Subjects
Adult
Biomarkers
Blood - metabolism
Collagen - metabolism
Humans
Hydrocortisone - blood
Male
Muscles - metabolism
Physical Exertion
Testosterone - blood
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Summary:The effect of an acute bout of high-intensity concentric exercise on serum muscle and collagen marker proteins was studied in nine male students. The muscle-derived serum carbonic anhydrase III, myoglobin, and creatine kinase all increased as a result of the exercise. Serum type I procollagen carboxyterminal propeptide decreased at first but started to increase 2 days after the exercise. Serum galactosylhydroxylysyl glucosyltransferase was elevated immediately after the exercise. No significant changes were seen in the concentrations of serum amino-terminal propeptide of type III procollagen or 4-hydroxyproline. It seems that a single bout of heavy concentric exercise causes protein leakage from muscles and probably from the collagen-synthesizing cells of the connective tissue, which may be accompanied by an initial decrease and a subsequent increase in type I collagen production. The activation of type I collagen production seems to depend on the strain and damage of the musculoskeletal system.
ISSN:8750-7587
DOI:10.1152/jappl.1993.75.3.1272