In Vitro Comparative Effect of Three Novel Borate Bioglasses on the Behaviors of Osteoblastic MC3T3-E1 Cells

Most related investigations focused on the effects of borate glass on cell proliferation/biocompatibility in vitro or bone repair in vivo; however, very few researches were carried out on other cell behaviors. Three novel borate bioglasses were designed as scaffolds for bone regeneration in this wok...

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Published inJournal of materials science & technology Vol. 30; no. 10; pp. 979 - 983
Main Authors Wei, Xiaojuan, Xi, Tingfei, Zheng, Yufeng, Zhang, Changqing, Huang, Wenhai
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.10.2014
Subjects
Biocompatibility
Bioglass
Biomedical materials
Bones
Borate bioglass
Borates
Cell behavior
Comparative study
In vitro testing
In vitro
Osteoblastic cells
Secretions
Surgical implants
体外
成骨细胞
生物相容性
硼酸盐玻璃
细胞增殖
细胞相容性
蛋白质分泌
行为
Borate bioglass
In vitro
Osteoblastic cells
Cell behavior
Comparative study
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Summary:Most related investigations focused on the effects of borate glass on cell proliferation/biocompatibility in vitro or bone repair in vivo; however, very few researches were carried out on other cell behaviors. Three novel borate bioglasses were designed as scaffolds for bone regeneration in this wok. Comparative effects of three bioglasses on the behaviors of osteoblastic MC3T3-E1 cells were evaluated. Excellent cytocompatibility of these novel borate bioglasses were approved in this work. Meanwhile, the promotion on cell proliferation, protein secretion and migration with minor cell apoptosis were also discussed in details, which contributed to the potential clinical application as a new biomaterial for orthopedics.
Bibliography:Comparative study; Borate bioglass; Osteoblastic cells; Cell behavior; In vitro
21-1315/TG
Most related investigations focused on the effects of borate glass on cell proliferation/biocompatibility in vitro or bone repair in vivo; however, very few researches were carried out on other cell behaviors. Three novel borate bioglasses were designed as scaffolds for bone regeneration in this wok. Comparative effects of three bioglasses on the behaviors of osteoblastic MC3T3-E1 cells were evaluated. Excellent cytocompatibility of these novel borate bioglasses were approved in this work. Meanwhile, the promotion on cell proliferation, protein secretion and migration with minor cell apoptosis were also discussed in details, which contributed to the potential clinical application as a new biomaterial for orthopedics.
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SourceType-Scholarly Journals-1
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ISSN:1005-0302
1941-1162
DOI:10.1016/j.jmst.2014.07.007