Extrapulmonary Tuberculosis: An Otorhinolaryngologist’s Perspective

• Published in: Indian journal of otolaryngology, and head, and neck surgery Vol. 74; no. Suppl 3; pp. 5562 - 5568
• Main Authors: Thomas, Nittu, Nambiar, Sapna Sreedharan, Nampoothiri, P. Muraleedharan
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.12.2022; Springer Nature B.V
• Subjects: Head and Neck Surgery; Medicine; Medicine & Public Health; Original; Original Article; Otolaryngology; Otorhinolaryngology; Tuberculosis; Anti tuberculous treatment (ATT); Extrapulmonary tuberculosis (EPTB); Tuberculous lymphadenopathy; Tuberculous laryngitis; Tuberculous otitis media
• ISSN: 2231-3796; 0973-7707
• DOI: 10.1007/s12070-021-02903-3

Objective The study aimed to determine the clinical manifestations and epidemiology of extrapulmonary tuberculosis (EPTB) of the head and neck in the otorhinolaryngeal regions. There is an increase in the incidence of EPTB in recent years because of increase in immunocompromised states and development of resistant bacteria. The clinical symptoms and signs of EPTB of the otorhinolaryngeal regions overlap with that of malignancies and other diseases in otorhinolaryngology thereby requiring correct early diagnosis so as to avoid unnecessary surgeries and procedures with initiation of appropriate anti tuberculous treatment under RNTCP. Study design Our prospective study was done on 45 patients who attended the ENT OPD at a tertiary care centre in Southern India over a period of 18 months with diagnosed EPTB of the otorhinolaryngeal regions. Results The study included 29 (64.4%) patients who presented with cervical lymphadenopathy, 11 (24.4%) patients with tuberculous laryngitis, 3 (6.6%) patients with tuberculous otitis media and 1 each with nasal and oral cavity tuberculosis. In our study 6 (13.3%) patients had co-existing pulmonary tuberculosis, 8 (18%) had diabetes, 5 (11%) had past history of tuberculosis and 7 (16%) had contact with patient with tuberculosis. Conclusion A high index of suspicion of EPTB must be kept among patients where (i) the clinical symptoms are out of proportion to the signs, (ii) common treatment fails or (iii) there is persistence or recurrence of symptoms despite therapy. The challenge is in confirming diagnosis which requires histopathological examination (HPE) of the tissue specimen. The timely diagnosis and initiation of anti tuberculous treatment (ATT) as per RNTCP helps in complete recovery thereby reducing morbidity.