Pituitary adenoma & nuclear medicine: Recent outcomes and ongoing developments

In order to explore pituitary adenoma (PA), magnetic resonance imaging (MRI) remains the cornerstone. However, there are some limitations and MRI can be non-conclusive. The development of additional imaging modalities like nuclear medicine explorations may help to confirm PA diagnosis, guide managem...

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Published inLa Presse médicale (1983) Vol. 51; no. 2; p. 104144
Main Authors Chevalier, Benjamin, Jannin, Arnaud, Espiard, Stephanie, Merlen, Emilie, Beron, Amandine, Lion, Georges, Vantyghem, Marie-Christine, Huglo, Damien, Cortet-Rudelli, Christine, Baillet, Clio
Format Journal Article
LanguageEnglish
Published France Elsevier Masson SAS 01.06.2022
Elsevier Masson
SeriesLa Presse Médicale
Subjects
Life Sciences
SR/SSTR
MRI
ACTH
NFPA
SPECT
18FDG
mTOR
FSH
THR
18FDOPA
SSA
CD
GH
PRRT
90Y
11C
18FET
68Ga
TSH
CS
PA
SUV
177Lu
CRH
LH
DA
PET
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Summary:In order to explore pituitary adenoma (PA), magnetic resonance imaging (MRI) remains the cornerstone. However, there are some limitations and MRI can be non-conclusive. The development of additional imaging modalities like nuclear medicine explorations may help to confirm PA diagnosis, guide management and follow up. Nuclear medicine uses radiopharmaceuticals for imaging with single photon emission computed tomography (SPECT), or positron emission tomography (PET), coupled to CT scan. Radiopharmaceuticals products target specific cellular elements which allow to explore several biological pathways. Nuclear medicine may also be used for therapeutic purposes and recent developments of approach based on Peptide Receptor Radionuclide Therapy (PRRT) for treatment of aggressive PA and pituitary carcinoma will be reviewed. Several radiotracers have been studied in the context of PA, and the aim of this paper is to discuss their respective performances and clinical interest.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0755-4982
2213-0276
DOI:10.1016/j.lpm.2022.104144