Subjective Cognitive Complaints: Predictors and Health Outcomes in People Living with HIV

There is a paucity of research on the prevalence of subjective cognitive complaints in people living with human immunodeficiency virus, along with the predictors and outcomes related to these complaints. We assessed demographics, substance use and psychiatric predictors, and HIV-related outcomes ass...

Full description

Saved in:
Bibliographic Details
Published inAIDS and behavior Vol. 26; no. 4; pp. 1163 - 1172
Main Authors Bryant, Vaughn E., Fieo, Robert A., Fiore, Andrew J., Richards, Veronica L., Porges, Eric C., Williams, Renessa, Lu, Huiyin, Zhou, Zhi, Cook, Robert L.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.04.2022
Springer Nature B.V
Subjects
Alcohol
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Anxiety - epidemiology
Bivariate analysis
Cannabis
Cognition
Cognition & reasoning
Cognitive ability
Demographics
Demography
Depression - epidemiology
Depression - psychology
Drinking behavior
Drug abuse
Health Psychology
HIV
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - epidemiology
Human immunodeficiency virus
Humans
Infectious Diseases
Marijuana
Marijuana Use
Medicine
Medicine & Public Health
Mental depression
Neurological disorders
Original Paper
Outcome Assessment, Health Care
Pathophysiology
Post traumatic stress disorder
Public Health
Regression analysis
Regression models
Substance abuse
Substance use
Adherence
Depression
Subjective cognitive complaints
ART
HIV
Online AccessGet full text

Cover

More Information
Summary:There is a paucity of research on the prevalence of subjective cognitive complaints in people living with human immunodeficiency virus, along with the predictors and outcomes related to these complaints. We assessed demographics, substance use and psychiatric predictors, and HIV-related outcomes associated with subjective cognitive complaint items from the Cognitive Difficulties Scale. The sample consisted of 889 people living with HIV in the survey-based Florida Cohort. Results of multivariable regression models indicated that age (45–54), hazardous alcohol consumption, more frequent marijuana use and psychiatric symptoms (depression, anxiety, PTSD) were significant predictors of subjective cognitive complaints. Subjective cognitive complaints were associated with lower adherence to antiretroviral therapy in bivariate analyses, but this relationship was no longer significant after controlling for depression, race, alcohol and drug use. Further research into the relationship between depressive and subjective cognitive complaints may provide additional avenues for intervention.
Bibliography:Author Contribution All authors contributed to the study conception and design. Data analysis was conducted by RF, HL, VB and ZZ. The first draft of the manuscript was written by VB and RF. Review and editing was conducted by all other authors. Additionally, all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-021-03469-5