Research-IQ: Development and evaluation of an ontology-anchored integrative query tool

Investigators in the translational research and systems medicine domains require highly usable, efficient and integrative tools and methods that allow for the navigation of and reasoning over emerging large-scale data sets. Such resources must cover a spectrum of granularity from bio-molecules to po...

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Bibliographic Details
Published inJournal of biomedical informatics Vol. 44; no. Suppl 1; pp. S56 - S62
Main Authors Borlawsky, Tara B., Lele, Omkar, Payne, Philip R.O.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.12.2011
Subjects
Clinical and translational research
Construction equipment
Databases, Factual
Design engineering
Effectiveness
Information retrieval
Information Storage and Retrieval - methods
Knowledge discovery
Knowledge engineering
Navigation
Phenotype
Query processing
Semantic web
Software
Translational Medical Research
Semantic web
Clinical and translational research
Information retrieval
Knowledge discovery
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Summary:Investigators in the translational research and systems medicine domains require highly usable, efficient and integrative tools and methods that allow for the navigation of and reasoning over emerging large-scale data sets. Such resources must cover a spectrum of granularity from bio-molecules to population phenotypes. Given such information needs, we report upon the initial design and evaluation of an ontology-anchored integrative query tool, Research-IQ, which employs a combination of conceptual knowledge engineering and information retrieval techniques to enable the intuitive and rapid construction of queries, in terms of semi-structured textual propositions, that can subsequently be applied to integrative data sets. Our initial results, based upon both quantitative and qualitative evaluations of the efficacy and usability of Research-IQ, demonstrate its potential to increase clinical and translational research throughput.
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ISSN:1532-0464
1532-0480
DOI:10.1016/j.jbi.2011.07.006