Reduced bladder capacity in patients receiving intravesical chemoprophylaxis with mitomycin C
After complete resection of superficial bladder carcinoma (Tis-2, G1-3), 75 patients were treated prophylactically with either 20 or 30 mg mitomycin C. Six patients developed a substantial reduction in bladder capacity (less than 200 ml). In 2 patients radical cystectomy of an otherwise tumour-free...
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Published in | British journal of urology Vol. 66; no. 4; p. 386 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
England
01.10.1990
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Subjects | |
Online Access | Get more information |
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Summary: | After complete resection of superficial bladder carcinoma (Tis-2, G1-3), 75 patients were treated prophylactically with either 20 or 30 mg mitomycin C. Six patients developed a substantial reduction in bladder capacity (less than 200 ml). In 2 patients radical cystectomy of an otherwise tumour-free fibrotic bladder was necessary. The results of long-term treatment (2 years) suggest that reduced bladder capacity correlates with the cumulative dosage of mitomycin C. |
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ISSN: | 0007-1331 |
DOI: | 10.1111/j.1464-410X.1990.tb14959.x |