Phytochemical analysis of Gymnema sylvestre and evaluation of its antimicrobial activity

Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The ro...

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Published inNatural product research Vol. 27; no. 6; pp. 583 - 587
Main Authors Chodisetti, Bhuvaneswari, Rao, Kiranmayee, Giri, Archana
Format Journal Article
LanguageEnglish
Published England Taylor & Francis Group 01.03.2013
Subjects
acetone
Alkanes - chemistry
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
anti-infective properties
antimicrobial activity
Bacteria - drug effects
chloroform
ethyl ether
G. sylvestre
Gas Chromatography-Mass Spectrometry
GC-MS
Gymnema sylvestre
Gymnema sylvestre - chemistry
MIC
minimum inhibitory concentration
oleic acid
Oleic Acid - chemistry
pathogens
Plant Components, Aerial - chemistry
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Roots - chemistry
root extracts
saponins
stigmasterol
Stigmasterol - chemistry
vitamin E
Vitamin E - chemistry
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Abstract Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL −1 and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.
AbstractList Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL(-1) and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL(-1) and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.
Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL super(-1) and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.
Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL −1 and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.
Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL(-1) and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.
Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04–1.28 mg mL⁻¹ and 0.08–2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.
Author Giri, Archana
Rao, Kiranmayee
Chodisetti, Bhuvaneswari
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Snippet Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The...
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SubjectTerms acetone
Alkanes - chemistry
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
anti-infective properties
antimicrobial activity
Bacteria - drug effects
chloroform
ethyl ether
G. sylvestre
Gas Chromatography-Mass Spectrometry
GC-MS
Gymnema sylvestre
Gymnema sylvestre - chemistry
MIC
minimum inhibitory concentration
oleic acid
Oleic Acid - chemistry
pathogens
Plant Components, Aerial - chemistry
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Roots - chemistry
root extracts
saponins
stigmasterol
Stigmasterol - chemistry
vitamin E
Vitamin E - chemistry
Title Phytochemical analysis of Gymnema sylvestre and evaluation of its antimicrobial activity
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