A cast of shadow on adjuvant radiotherapy for prostate cancer: A critical review based on a methodological perspective

Highlights • We focused on the applicability of data from RCTs in daily clinical practice. • We have employed an analytical framework based on PICO criteria to refine the search. • We analyzed 3 large RCTs regarding the use of RT after RP as adjuvant therapy. • We concluded that the role of adjuvant...

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Published inCritical reviews in oncology/hematology Vol. 97; pp. 322 - 327
Main Authors Arcangeli, Stefano, Ramella, Sara, De Bari, Berardino, Franco, Pierfrancesco, Alongi, Filippo, D’Angelillo, Rolando M
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.01.2016
Subjects
Combined Modality Therapy
Disease-Free Survival
Hematology, Oncology and Palliative Medicine
Humans
Male
Prostatectomy - methods
Prostatic Neoplasms - mortality
Prostatic Neoplasms - radiotherapy
Prostatic Neoplasms - surgery
Radiotherapy, Adjuvant
Randomized Controlled Trials as Topic
Survival Rate
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Summary:Highlights • We focused on the applicability of data from RCTs in daily clinical practice. • We have employed an analytical framework based on PICO criteria to refine the search. • We analyzed 3 large RCTs regarding the use of RT after RP as adjuvant therapy. • We concluded that the role of adjuvant RT could be reconsidered.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1040-8428
1879-0461
DOI:10.1016/j.critrevonc.2015.09.005