Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent

A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. [Display omitted]

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Bibliographic Details
Published inTetrahedron Vol. 69; no. 12; pp. 2628 - 2632
Main Authors Lin, Xiaoxi, Wang, Guimei, Li, Huaifeng, Huang, Yuanyuan, He, Weiming, Ye, Dandan, Huang, Kuo-Wei, Yuan, Yaofeng, Weng, Zhiqiang
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 25.03.2013
Elsevier
Subjects
Aryltrifluoromethylsulphones
chemical reactions
chemical structure
Chemistry
Chemistry, Organic
Compatibility
Copper catalyst
Electrophilic trifluoromethylation reaction
Functional groups
organic compounds
Physical Sciences
salts
Science & Technology
Tetrahedrons
Electrophilic trifluoromethylation reaction
Aryltrifluoromethylsulphones
Copper catalyst
PALLADIUM
2-PHOTON ABSORPTION
ARENES
TERMINAL ALKYNES
FLUORINATION
OXIDATIVE TRIFLUOROMETHYLATION
PERFLUOROALKYLATION
BORONIC ACIDS
Arykrifluoromethylsulphones
ARYL IODIDES
MEDIATED REDUCTIVE TRIFLUOROMETHYLATION
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Summary:A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. [Display omitted]
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2013.01.041