Chromosome Biology: Conflict Management for Replication and Transcription

A recent study has uncovered a new mechanism that attenuates DNA replication during periods of heightened gene expression to avoid collisions between replication and transcription.

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Bibliographic Details
Published inCurrent biology Vol. 23; no. 5; pp. R200 - R202
Main Authors Dewar, James M., Walter, Johannes C.
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 04.03.2013
Subjects
DNA Replication
Gene Expression Regulation, Fungal
Genome, Fungal - genetics
Mitogen-Activated Protein Kinases - metabolism
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae - metabolism
Saccharomyces cerevisiae Proteins - metabolism
Transcription, Genetic
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Summary:A recent study has uncovered a new mechanism that attenuates DNA replication during periods of heightened gene expression to avoid collisions between replication and transcription.
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ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2013.01.054