Outbreak of herpangina in the Brazilian Amazon in 2009 caused by Enterovirus B

• Published in: Archives of virology Vol. 159; no. 5; pp. 1155 - 1157
• Main Authors: Oliveira, D. B, Campos, R. K, Soares, M. S, Barros, R. B, Batista, T. C. A, Ferreira, P. C. P, Bonjardim, C. A, Trindade, G. S, Abrahão, J. S, Kroon, Erna Geessien
• Format: Journal Article
• Language: English
• Published: Vienna Springer-Verlag 01.05.2014; Springer Vienna; Springer Nature B.V
• Subjects: Adult; Biomedical and Life Sciences; Biomedicine; Brazil; Brief Report; Child; Child, Preschool; children; Disease Outbreaks; Enterovirus; Enterovirus B; Enterovirus B, Human - genetics; Enterovirus B, Human - isolation & purification; Enterovirus Infections - epidemiology; Enterovirus Infections - pathology; Enterovirus Infections - virology; Epidemics; etiological agents; Etiology; Herpangina - epidemiology; Herpangina - pathology; Herpangina - virology; Humans; Infant; Infections; Infectious Diseases; Medical Microbiology; Meningitis; patients; Phylogenetics; Phylogeny; Public health; Virology; Amazonia; Brazil; United States > US; Amazon Basin; South America, Amazon R; Picornavirus; Herpangina; Enterovirus B
• ISSN: 0304-8608; 1432-8798
• DOI: 10.1007/s00705-013-1858-5

In October 2009, our laboratory was contacted by a Brazilian Public Health organization regarding a severe community outbreak of an acute exanthematic and febrile disease in the Brazilian Amazon that primarily affected children. A total of 44 patients with febrile disease were identified by the local public health system, 37 of whom were children between 1 and 9 years of age. Molecular virological and phylogenetic characterization revealed that enterovirus B was the etiological agent of this outbreak, which was characterized by a clinical presentation known as herpangina.