Association of the neutrophil-to-lymphocyte ratio with the occurrence of venous thromboembolism and arterial thrombosis

• Published in: Journal of international medical research Vol. 52; no. 4; p. 3000605241240999
• Main Authors: Nguyen, Ha Thanh, Vu, Minh Phuong, Nguyen, Thi Tuyet Mai, Nguyen, Tuan Tung, Kieu, Thi Van Oanh, Duong, Hai Yen, Pham, Phuong Thao, Hoang, Thi Hue
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.04.2024; Sage Publications Ltd; SAGE Publishing
• Subjects: Lymphocytes; Neutrophils; Thromboembolism; Thrombosis; thrombosis; arterial thrombosis; Neutrophil-to-lymphocyte ratio; neutrophil; venous thromboembolism; lymphocyte
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/03000605241240999

Objective This study aimed to assess the association of the neutrophil-to-lymphocyte ratio (NLR) with the occurrence of venous thromboembolism (VTE) and arterial thrombosis (AT). Methods This was a retrospective cross-sectional study including 585 medical records obtained from all consecutive patients who were suspected of having thrombosis. Results The AT group had a higher neutrophil count and NLR and a lower lymphocyte count than the non-thrombosis group. Receiver operating characteristic curve analysis showed the ability of the NLR to predict the presence of AT. The cut-off value for the NLR was 4.44. No distinction was found in the NLR between the VTE and non-thrombosis groups. Regression analysis showed that a high NLR was an independent factor related to the presence of AT. Patients with an NLR ≥ 4.44 had a higher risk of AT than those with an NLR < 4.44 (odds ratio = 2.015, 95% confidence interval: 1.180–3.443). Conclusion A high NLR may be considered a predictive factor for the occurrence of AT, but an association with the presence of VTE was not found.