Chemotherapy-induced pneumatosis intestinalis followed by hepatic portal venous gas. A case report

Pneumatosis intestinalis (PI) is a rare disease, and there are many theories about its pathogenesis. Hepatic portal venous gas (HPVG), is thought to occur secondary to intramural intestinal gas emboli migrating through the portal venous system via the mesenteric veins. PI accompanied by HPVG is usua...

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Bibliographic Details
Published inJournal of international medical research Vol. 52; no. 3; p. 3000605241239276
Main Authors Pan, WenJun, Xiang, Shuai, Zhang, Junhao, Gao, Yuan, Liu, Shanglong
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.03.2024
Sage Publications Ltd
SAGE Publishing
Subjects
Antineoplastic Agents
Colorectal cancer
Embolism, Air - chemically induced
Embolism, Air - diagnostic imaging
Humans
Portal Vein - diagnostic imaging
Portal Vein - pathology
Pneumatosis intestinalis
Chemotherapy
Liver metastases
Hepatic portal venous gas
Colorectal cancer
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Summary:Pneumatosis intestinalis (PI) is a rare disease, and there are many theories about its pathogenesis. Hepatic portal venous gas (HPVG), is thought to occur secondary to intramural intestinal gas emboli migrating through the portal venous system via the mesenteric veins. PI accompanied by HPVG is usually a sign of bowel ischaemia and is associated with a high mortality rate. We report here, a patient with liver metastases from colorectal cancer who developed PI followed by HPVG after treatment with 5-Fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6). Timely attention and management of gastrointestinal symptoms following chemotherapy are essential in the treatment of this type of patient.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:0300-0605
1473-2300
DOI:10.1177/03000605241239276