Aryl fluorosulfates: powerful and versatile partners in cross-coupling reactions

Aryl fluorosulfates are versatile building blocks in organic synthesis and have gained increasing attention in SuFEx (Sulfur Fluoride Exchange) click chemistry. They are easily and conveniently prepared from phenols using sulfuryl fluoride SO 2 F 2 as a low-cost sulfonyl fluoride provider. Recently,...

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Bibliographic Details
Published inRSC advances Vol. 13; no. 2; pp. 13642 - 13654
Main Authors Saraswat, Shelesh Krishna, Seemaladinne, Ramanjaneyulu, Abdullah, Media Noori, Zaini, Halim, Ahmad, Nabeel, Ahmad, Nafis, Vessally, Esmail
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 02.05.2023
The Royal Society of Chemistry
Subjects
Aromatic compounds
Carbon
Chemical reactions
Chemical synthesis
Chemistry
Cross coupling
Phenols
Sulfur fluorides
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Summary:Aryl fluorosulfates are versatile building blocks in organic synthesis and have gained increasing attention in SuFEx (Sulfur Fluoride Exchange) click chemistry. They are easily and conveniently prepared from phenols using sulfuryl fluoride SO 2 F 2 as a low-cost sulfonyl fluoride provider. Recently, they served as less toxic and more atom economical alternatives to triflates in an impressive number of carbon-carbon and carbon-heteroatom cross-coupling reactions. In this review, we summarize the current advances and developments in applying aryl fluorosulfates as electrophilic partners in cross-coupling reactions. Aryl fluorosulfates are versatile building blocks in organic synthesis and have gained increasing attention in SuFEx (Sulfur Fluoride Exchange) click chemistry.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:2046-2069
2046-2069
DOI:10.1039/d3ra01791e