Graphene quantum dots for biosensing and bioimaging

Graphene Quantum Dots (GQDs) are low dimensional carbon based materials with interesting physical, chemical and biological properties that enable their applications in numerous fields. GQDs possess unique electronic structures that impart special functional attributes such as tunable optical/electri...

Full description

Saved in:
Bibliographic Details
Published inRSC advances Vol. 14; no. 23; pp. 161 - 1623
Main Authors Rasheed, P. Abdul, Ankitha, Menon, Pillai, Vijayamohanan K, Alwarappan, Subbiah
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 15.05.2024
The Royal Society of Chemistry
Subjects
Biological properties
Chemistry
Electrical properties
Graphene
Heavy metals
Hydrogen peroxide
Ions
Magnetic resonance imaging
Medical imaging
Optical properties
Peroxidase
Photoluminescence
Quantum dots
Surface properties
Online AccessGet full text

Cover

More Information
Summary:Graphene Quantum Dots (GQDs) are low dimensional carbon based materials with interesting physical, chemical and biological properties that enable their applications in numerous fields. GQDs possess unique electronic structures that impart special functional attributes such as tunable optical/electrical properties in addition to heteroatom-doping and more importantly a propensity for surface functionalization for applications in biosensing and bioimaging. Herein, we review the recent advancements in the top-down and bottom-up approaches for the synthesis of GQDs. Following this, we present a detailed review of the various surface properties of GQDs and their applications in bioimaging and biosensing. GQDs have been used for fluorescence imaging for visualizing tumours and monitoring the therapeutic responses in addition to magnetic resonance imaging applications. Similarly, the photoluminescence based biosensing applications of GQDs for the detection of hydrogen peroxide, micro RNA, DNA, horse radish peroxidase, heavy metal ions, negatively charged ions, cardiac troponin, etc. are discussed in this review. Finally, we conclude the review with a discussion on future prospects. This review covers recent advancements in the synthesis of graphene quantum dots (GQDs) and their properties. It highlights GQDs' applications in bioimaging for tumor visualization and MRI, as well as in various biosensing technologies.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ISSN:2046-2069
2046-2069
DOI:10.1039/d4ra01431f