The Use of High-Dose Hydroxocobalamin for Vasoplegic Syndrome

We describe a case of hypotension on cardiopulmonary bypass for coronary artery bypass grafting, double valve repairs, and patent foramen ovale closure. The patient experienced vasoplegic syndrome while on cardiopulmonary bypass. He was treated with high-dose hydroxocobalamin (vitamin B12 ). His blo...

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Bibliographic Details
Published inThe Annals of thoracic surgery Vol. 97; no. 5; pp. 1785 - 1786
Main Authors Roderique, Joseph D., MA, MS, VanDyck, Kofi, MD, Holman, Brita, MD, Tang, Daniel, MD, Chui, Betty, CCP, RN, Spiess, Bruce D., MD, FAHA
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 01.05.2014
Subjects
Cardiopulmonary Bypass - adverse effects
Cardiopulmonary Bypass - methods
Cardiothoracic Surgery
Combined Modality Therapy
Coronary Artery Bypass - adverse effects
Coronary Artery Bypass - methods
Foramen Ovale, Patent - surgery
Heart Valve Diseases - surgery
Heart Valve Prosthesis Implantation - adverse effects
Heart Valve Prosthesis Implantation - methods
Humans
Hydroxocobalamin - therapeutic use
Intraoperative Complications - diagnosis
Intraoperative Complications - drug therapy
Male
Middle Aged
Pulse Therapy, Drug
Surgery
Treatment Outcome
Vasoplegia - drug therapy
Vasoplegia - etiology
25
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Summary:We describe a case of hypotension on cardiopulmonary bypass for coronary artery bypass grafting, double valve repairs, and patent foramen ovale closure. The patient experienced vasoplegic syndrome while on cardiopulmonary bypass. He was treated with high-dose hydroxocobalamin (vitamin B12 ). His blood pressure responded rapidly, obviating any further vasopressor requirements.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0003-4975
1552-6259
DOI:10.1016/j.athoracsur.2013.08.050