Anhydrobiosis: Drying Out with Sugar

The disaccharide trehalose is a major determinant of desiccation tolerance via unresolved mechanisms. A new study highlights a critical role for this chemical chaperone in energy-independent maintenance of protein homeostasis during extended periods of dehydration and relative metabolic inactivity....

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Bibliographic Details
Published inCurrent biology Vol. 24; no. 23; pp. R1121 - R1123
Main Author Morano, Kevin A.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2014
Subjects
Decapoda
Nematoda
Rotifera
Saccharomyces cerevisiae
Saccharomyces cerevisiae - physiology
Trehalose - metabolism
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Summary:The disaccharide trehalose is a major determinant of desiccation tolerance via unresolved mechanisms. A new study highlights a critical role for this chemical chaperone in energy-independent maintenance of protein homeostasis during extended periods of dehydration and relative metabolic inactivity. The disaccharide trehalose is a major determinant of desiccation tolerance via unresolved mechanisms. A new study highlights a critical role for this chemical chaperone in energy-independent maintenance of protein homeostasis during extended periods of dehydration and relative metabolic inactivity.
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ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2014.10.022