Synthesis and Antinociceptive Activity of (5-Chloro-2-benzothiazolinon-3-yl)acetamide Derivatives

The synthesis of (5‐chloro‐2‐benzothiazolinon‐3‐yl)acetamide derivatives is reported. The structure of these compounds is supported by their IR and 1H‐NMR spectra. The compounds were tested for antinociceptive activity.

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Bibliographic Details
Published inArchiv der Pharmazie (Weinheim) Vol. 333; no. 10; pp. 337 - 340
Main Authors Önkol, T., Dogruer, D. S., Ito, S., Sahin, M. F.
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag GmbH 01.10.2000
WILEY‐VCH Verlag GmbH
Wiley
Wiley-VCH
Subjects
(5-Chloro-2-benzothiazolinon-3-yl)acetamide
Analgesics
Analgesics - chemical synthesis
Animals
antinociceptive activity
Benzothiazoles
Biological and medical sciences
Chemistry
Chemistry, Medicinal
Chemistry, Multidisciplinary
Life Sciences & Biomedicine
Male
Medical sciences
Mice
Neuropharmacology
NMR
Pharmacology & Pharmacy
Pharmacology. Drug treatments
Physical Sciences
Piperazines - chemical synthesis
Piperazines - pharmacology
Science & Technology
Structure-Activity Relationship
(5-chloro-2-benzothiazolinon-3-yl)acetamide antiociceptive activity
NMR
Sulfur nitrogen heterocycle
Rodentia
Benzothiazole derivatives
Vertebrata
Mammalia
Analgesic
Structure activity relation
Mouse
Animal
Chlorine Organic compounds
Bicyclic compound
Carboxamide
Aromatic compound
Chemical synthesis
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Summary:The synthesis of (5‐chloro‐2‐benzothiazolinon‐3‐yl)acetamide derivatives is reported. The structure of these compounds is supported by their IR and 1H‐NMR spectra. The compounds were tested for antinociceptive activity.
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ArticleID:ARDP337
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0365-6233
1521-4184
DOI:10.1002/1521-4184(200010)333:10<337::AID-ARDP337>3.0.CO;2-A