A case of mottled hypopigmentation after low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet laser therapy

Abstract Melasma is a very difficult pigmented disease to treat with high recurrence rate. Using low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet (QSNY) lasers repeatedly for the treatment of melasma is now a common practice in East Asia. However, one of the significant side e...

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Bibliographic Details
Published inJournal of cosmetic and laser therapy Vol. 15; no. 5; pp. 290 - 292
Main Authors Ryu, Hwa Jung, Kim, Jiehoon
Format Journal Article
LanguageEnglish
Published England Informa Healthcare 01.10.2013
Subjects
Female
Humans
Hypopigmentation - etiology
Lasers, Solid-State - adverse effects
Lasers, Solid-State - therapeutic use
Low-Level Light Therapy - adverse effects
Melanosis - radiotherapy
Middle Aged
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Summary:Abstract Melasma is a very difficult pigmented disease to treat with high recurrence rate. Using low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet (QSNY) lasers repeatedly for the treatment of melasma is now a common practice in East Asia. However, one of the significant side effects is mottled hypopigmentation that appears as scattered white macules in the middle of melasma lesion. The pathophysiology of these hypopigmentation is yet unknown. The biopsy of the hypopigmented lesion showed decreased melanosome with intact melanocytes, and topical tretinoin may be the effective solution for these types of condition.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:1476-4172
1476-4180
DOI:10.3109/14764172.2013.769762