Mammalian epididymal proteome

In all mammalian species, the final differentiation of the male germ cell occurs in the epididymal duct where the spermatozoa develop the ability to be motile and fertilize an ovum. Understanding of these biological processes is the key to understanding and controlling male fertility. Comparative st...

Full description

Saved in:
Bibliographic Details
Published inMolecular and cellular endocrinology Vol. 306; no. 1; pp. 45 - 50
Main Authors Dacheux, Jean-Louis, Belleannée, Clémence, Jones, Russell, Labas, Valérie, Belghazi, Maya, Guyonnet, Benoît, Druart, Xavier, Gatti, Jean Luc, Dacheux, Françoise
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 10.07.2009
Elsevier
Subjects
Animals
Body Fluids - metabolism
Epididymis
Epididymis - metabolism
Humans
Male
Mammals - metabolism
Proteome
Proteome - metabolism
Secretome
Species Specificity
Sperm Maturation
Proteome
Epididymis
Secretome
Sperm maturation
Online AccessGet full text

Cover

More Information
Summary:In all mammalian species, the final differentiation of the male germ cell occurs in the epididymal duct where the spermatozoa develop the ability to be motile and fertilize an ovum. Understanding of these biological processes is the key to understanding and controlling male fertility. Comparative studies between several mammals could be an informative approach to finding common sperm modifications which are not species-specific. The new global biological approaches such as transcriptomes and proteomes provide considerable information which can be used for such comparative approaches. This report summarizes our proteomic studies of the epididymis of several mammals, including humans.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0303-7207
1872-8057
0303-7207
DOI:10.1016/j.mce.2009.03.007