A case of isolated amyloidosis in extraocular muscle mimicking thyroid eye disease

A 24-year-old woman presented with periorbital pain, progressive diplopia, and restricted eye movement. Routine blood testing was normal except for increased levels of thyroid peroxidase autoantibody (TPOAb) and thyroglobulin autoantibody (TGAb). Orbital computed tomography revealed fusiform thicken...

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Bibliographic Details
Published inJournal of AAPOS Vol. 24; no. 2; pp. 122 - 124
Main Authors Li, YuePing, Wang, Yuchuan, Zhang, Wei
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.04.2020
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Summary:A 24-year-old woman presented with periorbital pain, progressive diplopia, and restricted eye movement. Routine blood testing was normal except for increased levels of thyroid peroxidase autoantibody (TPOAb) and thyroglobulin autoantibody (TGAb). Orbital computed tomography revealed fusiform thickening of the rectus muscles belly, with tendon sparing, as in thyroid eye disease. Rectus muscle biopsy revealed isolated amyloidosis. Further workup showed no evidence of systemic amyloidosis.▪
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:1091-8531
1528-3933
DOI:10.1016/j.jaapos.2019.12.009