Acute effects of beating heart coronary surgery on left ventricular performance

• Published in: The Annals of thoracic surgery Vol. 74; no. 4; pp. 1348 - 1352
• Main Authors: Torracca, Lucia, Schreuder, Jan J, Quarti, Andrea, Ismeno, Gennaro, Franzé, Vincenzo, Alfieri, Ottavio
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01.10.2002; Elsevier Science
• Subjects: Aged; Biological and medical sciences; Blood Pressure; Cardiac Volume; Cardiopulmonary Bypass; Coronary Artery Bypass - methods; Female; Heart Rate - physiology; Humans; Male; Medical sciences; Middle Aged; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Ventricular Function, Left - physiology; 28; Human; Treatment; Aortocoronary; Bypass; Surgery; Cardiovascular disease; Exploration; Hemodynamics; Left ventricle performance; Coronary heart disease
• ISSN: 0003-4975; 1552-6259
• DOI: 10.1016/S0003-4975(02)03973-5

The increasing use of off-pump bypass grafting (OPCABG), requires an evaluation of its effects on left ventricular (LV) performance. In 8 patients with multivessel coronary disease who were undergoing to off-pump coronary artery bypass grafting, LV performance was analyzed from the pressure–volume (P-V) plane by the conductance catheter technique. Measurements were performed at base line, after the exposure of the vessels, after the application of the stabilization system, and at the end of the procedure. No significant changes in heart rate, LV end-systolic volume, LV end-diastolic pressure, mean pulmonary artery, and mean systemic blood pressure were observed in the various stages of the procedure. Cardiac index decreased during left anterior descending coronary artery grafting after application of the stabilizer with a concomitant decrease in LV end-diastolic volume, together with decreases in LV peak negative −dP/dt and increases in τ, indicating an impairment of LV relaxation but without a change in preload recruitable stroke work, indicating preserved LV contractile state. Exposure of posterior and lateral vessels induced a decrease in cardiac index and preload recruitable stroke work without a decrease in LV preload, indicating a decrease in LV contractile state together with a decrease in peak −dP/dt and increase in τ, indicating an impairment in LV relaxation Off-pump coronary artery bypass grafting can be performed without decreasing LV performance. Major cardiac displacement like that used for posterior and lateral exposure induces acutely significant decrease in LV contractile state.