The active constituents from Gualou-xiebai-baijiu-tang part I: Active saponins

• Published in: Journal of asian natural products research Vol. 4; no. 3; pp. 189 - 196
• Main Authors: He, Xiang-Jiu, Qiu, Feng, Shoyama, Yukihiro, Tanaka, Hiroyoki, Yao, Xin-Sheng
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis Group 01.09.2002; Taylor & Francis
• Subjects: Allium; Allium Macrostemon Bge; Biological and medical sciences; Chemistry; Chemistry, Applied; Chemistry, Medicinal; General pharmacology; Gualou-xiebai-baijiu-tang; Humans; Life Sciences & Biomedicine; Medical sciences; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Physical Sciences; Phytotherapy; Plant Extracts - chemistry; Plant Extracts - isolation & purification; Plant Sciences; Saponins - chemistry; Saponins - isolation & purification; Science & Technology; Steroidal Saponins; Trichosanthes; Trichosanthes Kirilowii Maxim; Triterpenes - chemistry; Triterpenes - isolation & purification; Triterpenoidal Saponin; Asia; China; triterpenoidal saponin; GLYCOSIDES; Trichosanthes kirilowii Maxim; Gualou-xiebai-baijiu-tang; ALLIUM MACROSTEMON; steroidal saponins; Allium macrostemon Bge; SAPOGENINS; Pentacyclic compound; Steroid; Monocotyledones; Oxygen heterocycle; Disaccharide; Medicinal plant; Saponin; Acetal; Ester; Folk medicine; Dicotyledones; Angiospermae; Glycoside; Secondary alcohol; Terpenoid; Fruit; Pharmacognosy; Oriental medicine; Cucurbitaceae; Polycyclic compound; Hemiacetal; Spiran; Allium; Oleanane derivatives; Liliaceae; Bulb; Plant origin; Triterpene; Isolation; Spirostane derivatives; Spermatophyta; Glycol; Structural analysis
• ISSN: 1028-6020; 1477-2213
• DOI: 10.1080/10286020290011404

Two new steroidal saponins and a new triterpenoidal saponin, together with nine known steroidal saponins, were isolated from "Gualou-xiebai-baijiu-tang" consisting of Fructus trichosanthis and Bulbus allii macrostemi . The structures of the three new compounds were determined as 3- O - g - d -galactopyranosyl-hederagenin 28- O - g - d -xylopyranosyl (1 M 6)- g - d -galactopyranosyl ester ( 1 ), spirost 25(27)-ene-2 g ,3 g -diol-3- O - g - d -glucopyranosyl (1 M 2)- g - d -galactopyranoside ( 2 ) and 26- O - g - d -glucopyranosyl-22 f -hydroxy-5 g -furost-25(27)-ene-1 g ,3 g ,6 g ,26-tetraol-3- O - g - d -galactopyranoside ( 3 ), respectively, by means of chemical evidences and spectral analysis.