Synthesis of texaphyrin conjugates

This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strate...

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Published inPure and applied chemistry Vol. 76; no. 2; pp. 365 - 374
Main Authors Magda, D. J., Wang, Z., Gerasimchuk, Nikolay, Wei, W.-H., Anzenbacher, P., Sessler, J. L.
Format Journal Article
LanguageEnglish
Published Berlin De Gruyter 01.01.2004
Walter de Gruyter GmbH
Subjects
Anticancer properties
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Summary:This paper summarizes recent synthetic efforts devoted to the generation of new, second-generation texaphyrin-type drugs, specifically species that involve known or potential anticancer agents covalently attached to a tumor-localizing texaphyrin core. Particular emphasis will be placed on the strategies needed to prepare such systems, as well as on the choice of active group being subject to attachment.
ISSN:0033-4545
1365-3075
DOI:10.1351/pac200476020365