Systematic collection of patient-reported outcomes in atrial fibrillation: feasibility and initial results of the Utah mEVAL AF programme

• Published in: Europace (London, England) Vol. 22; no. 3; pp. 368 - 374
• Main Authors: Steinberg, Benjamin A, Turner, Jeffrey, Lyons, Ann, Biber, Joshua, Chelu, Mihail G, Fang, James C, Freedman, Roger A, Han, Frederick T, Hardisty, Benjamin, Marrouche, Nassir F, Ranjan, Ravi, Shah, Rashmee U, Spertus, John A, Stehlik, Josef, Zenger, Brian, Piccini, Jonathan P, Hess, Rachel
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.03.2020
• Subjects: Clinical Research; Feasibility; Patient-reported outcomes; Toronto Atrial Fibrillation Severity Scale; Atrial fibrillation; Quality of life
• ISSN: 1099-5129; 1532-2092
• DOI: 10.1093/europace/euz293

Abstract Aims Incorporating patient-reported outcomes (PROs) into routine care of atrial fibrillation (AF) enables direct integration of symptoms, function, and health-related quality of life (HRQoL) into practice. We report our initial experience with a system-wide PRO initiative among AF patients. Methods and results All patients with AF in our practice undergo PRO assessment with the Toronto AF Severity Scale (AFSS), and generic PROs, prior to electrophysiology clinic visits. We describe the implementation, feasibility, and results of clinic-based, electronic AF PRO collection, and compare AF-specific and generic HRQoL assessments. From October 2016 to February 2019, 1586 unique AF patients initiated 2379 PRO assessments, 2145 of which had all PRO measures completed (90%). The median completion time for all PRO measures per visit was 7.3 min (1st, 3rd quartiles: 6, 10). Overall, 38% of patients were female (n = 589), mean age was 68 (SD 12) years, and mean CHA2DS2-VASc score was 3.8 (SD 2.0). The mean AFSS symptom score was 8.6 (SD 6.6, 1st, 3rd quartiles: 3, 13), and the full range of values was observed (0, 35). Generic PROs of physical function, general health, and depression were impacted at the most severe quartiles of AF symptom score (P < 0.0001 for each vs. AFSS quartile). Conclusion Routine clinic-based, PRO collection for AF is feasible in clinical practice and patient time investment was acceptable. Disease-specific AF PROs add value to generic HRQoL instruments. Further research into the relationship between PROs, heart rhythm, and AF burden, as well as PRO-guided management, is necessary to optimize PRO utilization.