How well do we know Gradenigo? A comprehensive literature review and proposal for novel diagnostic categories of Gradenigo's syndrome
Gradenigo's Syndrome is a rare complication of otitis media and/or mastoiditis resulting in inflammation of the petrous apex of the temporal bone. Here, we highlight an interesting case from our institution, summarize available pediatric cases from the past fifty years to provide an updated dia...
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| Published in | International journal of pediatric otorhinolaryngology Vol. 132; p. 109942 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
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Ireland
Elsevier B.V
01.05.2020
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| Abstract | Gradenigo's Syndrome is a rare complication of otitis media and/or mastoiditis resulting in inflammation of the petrous apex of the temporal bone. Here, we highlight an interesting case from our institution, summarize available pediatric cases from the past fifty years to provide an updated diagnostic categorization for this rare condition with confusing nomenclature, and suggest guidance for diagnosis and management.
•Consider GS when acute CN VI palsy is present with at least one additional sign/symptom of the original GS triad.•Diagnosis should include urgent neuroimaging with contrast ± angiography.•Therapy should include broad spectrum antibiotics with CNS penetration ± surgery. |
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| AbstractList | Gradenigo's Syndrome is a rare complication of otitis media and/or mastoiditis resulting in inflammation of the petrous apex of the temporal bone. Here, we highlight an interesting case from our institution, summarize available pediatric cases from the past fifty years to provide an updated diagnostic categorization for this rare condition with confusing nomenclature, and suggest guidance for diagnosis and management.
•Consider GS when acute CN VI palsy is present with at least one additional sign/symptom of the original GS triad.•Diagnosis should include urgent neuroimaging with contrast ± angiography.•Therapy should include broad spectrum antibiotics with CNS penetration ± surgery. Gradenigo's Syndrome is a rare complication of otitis media and/or mastoiditis resulting in inflammation of the petrous apex of the temporal bone. Here, we highlight an interesting case from our institution, summarize available pediatric cases from the past fifty years to provide an updated diagnostic categorization for this rare condition with confusing nomenclature, and suggest guidance for diagnosis and management. |
| ArticleNumber | 109942 |
| Author | El Saleeby, Chadi M. McLaren, John Cohen, Michael S. |
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| Snippet | Gradenigo's Syndrome is a rare complication of otitis media and/or mastoiditis resulting in inflammation of the petrous apex of the temporal bone. Here, we... |
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| SubjectTerms | Child, Preschool Female Gradenigo's syndrome Humans Mastoiditis - complications Otitis Media - complications Pediatrics Petrositis - classification Petrositis - diagnosis Petrositis - etiology Petrous apicitis |
| Title | How well do we know Gradenigo? A comprehensive literature review and proposal for novel diagnostic categories of Gradenigo's syndrome |
| URI | https://dx.doi.org/10.1016/j.ijporl.2020.109942 https://www.ncbi.nlm.nih.gov/pubmed/32065876 https://search.proquest.com/docview/2357456911 |
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