Endoscopic therapy of benign pyloric stenosis and gastric outlet obstruction

• Published in: Current opinion in gastroenterology Vol. 22; no. 5; p. 570
• Main Authors: Yusuf, Tony E, Brugge, William R
• Format: Journal Article
• Language: English
• Published: United States 01.09.2006
• Subjects: Adult; Aged; Aged, 80 and over; Catheterization; Female; Gastric Outlet Obstruction - etiology; Gastric Outlet Obstruction - microbiology; Gastric Outlet Obstruction - therapy; Helicobacter Infections - complications; Helicobacter Infections - microbiology; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer - complications; Peptic Ulcer - microbiology; Pyloric Stenosis - etiology; Pyloric Stenosis - microbiology; Pyloric Stenosis - therapy; Treatment Outcome
• ISSN: 0267-1379
• DOI: 10.1097/01.mog.0000239874.13867.41

To examine the short and long-term success rates of balloon dilation of pyloric stenosis. Several large studies have demonstrated high rates of success for the relief of symptoms from pyloric stenosis using through-the-scope balloons. These dilating balloons readily increase the diameter of the stenotic pylorus on average from 6 to 16 mm. Patients who require more than two dilations are at high risk of endoscopic failure and the need for surgical intervention. Rapid re-stenosis rates are observed in patients with malignant pyloric obstruction. Since many patients with benign pyloric stenosis have underlying ulcer disease, helicobacter infection is a relatively common finding. Eradication of this infection at the time of balloon dilation will ensure higher long-term success rates. In summary, benign pyloric stenosis can be readily treated with endoscopic balloon dilation and should be the first-line therapy.