Hospitalizations for pulmonary embolism in Brazil (2008-2019): an ecological and time series study

• Published in: Jornal brasileiro de pneumologia Vol. 48; no. 3; p. e20210434
• Main Authors: Gomes, Jéssica Alves, Barros, José Elias Bezerra, Nascimento, André Luis Oliveira do, Rocha, Carlos Alberto de Oliveira, Almeida, João Paulo Oliveira de, Santana, Gibson Barros de Almeida, Correia, Divanise Suruagy, Santos, Márcio Bezerra, Carmo, Rodrigo Feliciano do, Souza, Carlos Dornels Freire de
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Pneumologia e Tisiologia 2022
• Subjects: Brazil - epidemiology; Ecological studies; Epidemiology; Hospital Mortality; Hospitalization; Humans; Original; Pulmonary embolism; Pulmonary Embolism - epidemiology; RESPIRATORY SYSTEM; Time Factors; Time series; Brazil; Pulmonary embolism; Séries cronológicas; Estudos ecológicos; Ecological studies; Embolia pulmonar; Time series; Epidemiologia; Epidemiology
• ISSN: 1806-3756; 1806-3713; 1806-3756
• DOI: 10.36416/1806-3756/e20210434

To assess the temporal trends of hospitalizations for pulmonary embolism (PE) in Brazil, its regions, and states between 2008 and 2019. An ecological and time series study was conducted. Data were obtained from the Hospital Information System (SIH) of the Brazilian Ministry of Health. The inflection point regression model was applied for temporal trend analyses. Trends were classified as increasing, decreasing, or stationary according to the slope of the regression line. The Annual Percent Charge (APC) and the Average Annual Percent Change (AAPC) were calculated considering a confidence interval of 95% and p-value <0.05. Furthermore, spatial distribution maps of epidemiological indicators related to PE in Brazil were elaborated. There was an increasing trend in the hospitalization rate for PE in Brazil, ranging from 2.57 in 2008 to 4.44/100,000 in 2019 (AAPC=5.6%; p<0.001). Total and average hospitalizations costs also showed increasing trend in the country (AAPC=9.2% and 3.0%, respectively). Still, there was a decrease in the in-hospital mortality rate (from 21.21% to 17.11%; AAPC=-1.9%; p<0.001). Similar trends were observed in most regions. The average hospitalization time in Brazil showed a stationary trend. The hospitalization rate has also increased in 18 states (66.67%). Seven states showed a decrease in the mortality rate (25.93%), except for Roraima, which showed an increasing trend. Hospitalizations for PE represent a serious public health problem in Brazil and the temporal patterns observed herein demonstrate an increasing trend in all regions and states of the country.