Beta testing the monkey model

Corbett et al. use the rhesus macaque model to evaluate the ability of the mRNA-1273 (Moderna) COVID-19 vaccine to protect against challenge with the antibody-evading Beta variant of SARS-CoV-2. Their key finding is that the vaccine prevents severe lung pathology, principally because it is able to i...

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Bibliographic Details
Published inNature immunology Vol. 22; no. 10; pp. 1201 - 1203
Main Authors Moore, John P, Gounder, Celine R
Format Journal Article
LanguageEnglish
Published United States Nature Publishing Group 01.10.2021
Subjects
COVID-19
COVID-19 vaccines
Monkeys & apes
mRNA
Severe acute respiratory syndrome coronavirus 2
Vaccines
United States
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Summary:Corbett et al. use the rhesus macaque model to evaluate the ability of the mRNA-1273 (Moderna) COVID-19 vaccine to protect against challenge with the antibody-evading Beta variant of SARS-CoV-2. Their key finding is that the vaccine prevents severe lung pathology, principally because it is able to induce a strong enough antibody resistance to overcome the variant's relative resistance.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Commentary-1
ISSN:1529-2908
1529-2916
DOI:10.1038/s41590-021-01033-w