Nature’s Antimicrobial Arsenal: Non-Ribosomal Peptides from PGPB for Plant Pathogen Biocontrol

• Published in: Fermentation (Basel) Vol. 9; no. 7; p. 597
• Main Authors: Ranjan, Anuj, Rajput, Vishnu D., Prazdnova, Evgeniya Valeryevna, Gurnani, Manisha, Bhardwaj, Pallavi, Sharma, Shikha, Sushkova, Svetlana, Mandzhieva, Saglara S., Minkina, Tatiana, Sudan, Jebi, Zargar, Sajad Majeed, Chauhan, Abhishek, Jindal, Tanu
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.07.2023
• Subjects: Antimicrobial agents; Bacteria; Bioactive compounds; Biological control; Crop diseases; disease; Disease control; Enzymes; Fatty acids; Food security; Fungi; microbes; Microorganisms; NRPs; Pathogens; Peptides; Physiological aspects; Plant diseases; plant pathogen; Plasmids; Reviews; sustainable agriculture; VOCs; Volatile organic compounds; Germany
• ISSN: 2311-5637; 2311-5637
• DOI: 10.3390/fermentation9070597

Non-ribosomal peptides (NRPs) are a diverse group of bioactive compounds synthesized by microorganisms, and their antimicrobial properties make them ideal candidates for use as biocontrol agents against pathogens. Non-ribosomal peptides produced by Plant-Growth-Promoting Bacteria (PGPB) have gained interest for the biocontrol of plants’ bacterial and fungal pathogens. In this review, the structure and mode of action of NRPs, including their characterization and the characterization of NRP-producing microorganisms, are discussed. The use of NRPs in soilless agriculture and their potential as part of a sustainable plant disease control strategy are also highlighted. In addition, the review debates the commercial aspects of PGPB’s formulations and their potential as a biocontrol agent. Overall, this review emphasizes the importance of NRPs derived from PGPB in the biocontrol of plant pathogens and their potential to be used as an environmentally friendly and sustainable plant disease control strategy.