Albuminuria reduction: The Holy Grail for Kidney Protection

Increased urinary excretion of albumin or total protein has become firmly established as a risk predictor for progression of chronic kidney disease. Observational analyses have raised a strong hypothesis that albuminuria reduction should be a clinical treatment target. Bakris et al. report further e...

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Bibliographic Details
Published inKidney international Vol. 72; no. 7; pp. 785 - 786
Main Author Tuttle, K.R.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2007
Elsevier Limited
Subjects
Albuminuria - drug therapy
Angiotensin II Type 1 Receptor Blockers - therapeutic use
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Biomarkers - urine
Biphenyl Compounds - therapeutic use
Humans
Ramipril - therapeutic use
Tetrazoles - therapeutic use
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Summary:Increased urinary excretion of albumin or total protein has become firmly established as a risk predictor for progression of chronic kidney disease. Observational analyses have raised a strong hypothesis that albuminuria reduction should be a clinical treatment target. Bakris et al. report further exploration of albuminuria-lowering capabilities of intensified renin–angiotensin system inhibition in a randomized clinical trial that included patients at high cardiovascular risk, most of whom appeared to have diabetic kidney disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Commentary-1
ISSN:0085-2538
1523-1755
DOI:10.1038/sj.ki.5002505