Clinical and Regulatory Considerations for Central Venous Catheters for Hemodialysis

• Published in: Clinical journal of the American Society of Nephrology Vol. 13; no. 12; pp. 1924 - 1932
• Main Authors: Silverstein, Douglas M, Trerotola, Scott O, Clark, Timothy, James, Garth, Ng, Wing, Dwyer, Amy, Florescu, Marius C, Shingarev, Roman, Ash, Stephen R
• Format: Journal Article
• Language: English
• Published: United States American Society of Nephrology 07.12.2018
• Subjects: Central Venous Catheters - adverse effects; Central Venous Catheters - standards; Equipment Design; Humans; Renal Dialysis - instrumentation; Risk Assessment; hemodialysis; dialysis access; hemodialysis access; end stage kidney disease; chronic dialysis
• ISSN: 1555-9041; 1555-905X
• DOI: 10.2215/CJN.14251217

Central venous catheters remain a vital option for access for patients receiving maintenance hemodialysis. There are many important and evolving clinical and regulatory considerations for all stakeholders for these devices. Innovation and transparent and comprehensive regulatory review of these devices is essential to stimulate innovation to help promote better outcomes for patients receiving maintenance hemodialysis. A workgroup that included representatives from academia, industry, and the US Food and Drug Administration was convened to identify the major design considerations and clinical and regulatory challenges of central venous catheters for hemodialysis. Our intent is to foster improved understanding of these devices and provide the foundation for strategies to foster innovation of these devices.