Tobacco Addiction: Implications for Treatment and Cancer Prevention

• Published in: JNCI : Journal of the National Cancer Institute Vol. 89; no. 24; pp. 1852 - 1867
• Main Authors: Cinciripini, Paul M., Hecht, Stephen S., Henningfield, Jack E., Manley, Marc W., Kramer, Barnett S.
• Format: Journal Article
• Language: English
• Published: Cary, NC Oxford University Press 17.12.1997; Oxford Publishing Limited (England)
• Subjects: Addictions; Biological and medical sciences; Conferences; Depression - complications; Epidemiology; Health Policy; Humans; Lung cancer; Medical sciences; National Institutes of Health (U.S.); Neoplasms - epidemiology; Neoplasms - etiology; Neoplasms - prevention & control; Risk Factors; Smoking Cessation; Societies, Medical; Tobacco; Tobacco Use Disorder - complications; Tobacco Use Disorder - epidemiology; Tobacco Use Disorder - psychology; Tobacco Use Disorder - therapy; Tumors; United States; United States; North America; America; Human; Prevention; Health policy; Treatment; Tobacco smoking; Malignant tumor; Epidemiology; Public health
• ISSN: 0027-8874; 1460-2105
• DOI: 10.1093/jnci/89.24.1852

The American Society of Clinical Oncology and the National Cancer Institute convened a symposium in June 1996 on tobacco addiction. Additional support for the symposium was provided by the American Medical Women's Association and the American Society of Preventive Oncology. The goals of this conference were to describe the burden and public health consequences of tobacco addiction, to describe the state of science for the treatment of nicotine dependence, and to explore new strategies to increase quit rates and to prevent the uptake of tobacco use. This article summarizes and integrates the meeting presentations on tobacco addiction and includes the topics of smoking prevalence; psychobiologic aspects of nicotine dependence; and implications for disease, treatment, and prevention. Comments on regulatory approaches and national strategies for reducing dependence are also summarized in presentations by Dr. David Kessler, former Food and Drug Administration Commissioner, and Dr. C. Everett Koop, former U.S. Surgeon General. “Tobacco drieth the brain, dimmeth the sight, vitiateth the smell, hurteth the stomach, destroyeth the concoction, disturbeth the humors and spirits, corrupteth the breath, induceth a trembling of the limbs, exsicateth the windpipe, lungs, and liver, annoyeth the milt, scortcheth the heart, and causeth the blood to be adjusted.” Tobias Verner, 1577-1660