Preliminary Report on the Effects of Propolis on Wound Healing in the Dental Pulp

• Published in: Zeitschrift für Naturforschung C. A journal of biosciences Vol. 53; no. 11; pp. 1045 - 1048
• Main Authors: Bretz, Walter A., Chiego, D. J., Marcucci, M. C., Cunha, I., Custódio, A., Schneider, L. G.
• Format: Journal Article
• Language: English
• Published: Germany Verlag der Zeitschrift für Naturforschung 01.12.1998
• Subjects: Animals; Antimicrobial; Apidae; Apis mellifera; Dental Materials; Dental Pulp; Dental Pulp - drug effects; Dental Pulp - physiopathology; Male; Propolis; Propolis - pharmacology; Rats; Rats, Wistar; Regeneration; Wound Healing; Wound Healing - drug effects
• ISSN: 0939-5075; 1865-7125
• DOI: 10.1515/znc-1998-11-1217

The purpose of this investigation was to determine the antimicrobial and healing potential of propolis on direct dental pulp exposures. This study used 25 adult male rats. Pulp expo­sures were performed and animals were allocated to propolis and calcium hydroxide (Ca(OH) groups. Animals were killed on days 5, 7, 10, and 14. The teeth were routinely processed for histological evaluation. Non-parametric tests were employed to analyze the data. No significant differences were found between study groups on the wound healing of the dental pulp. Both substances were com parable in exhibiting normal reorganization of the pulp and no increased vascularity, and were equally efficacious in maintaining a low inflammatory and microbial cell population as well as in stimulating the formation of reparative dentin.