AtMYB4: a transcription factor general in the battle against UV

• Published in: Trends in plant science Vol. 6; no. 4; pp. 135 - 136
• Main Authors: Hemm, Matthew R, Herrmann, Klaus M, Chapple, Clint
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.04.2001
• Subjects: Arabidopsis - genetics; Arabidopsis - metabolism; Arabidopsis Proteins; cinnamate 4-hydroxylase; Cytochrome P-450 Enzyme System - biosynthesis; Cytochrome P-450 Enzyme System - genetics; Cytochrome P-450 Enzyme System - metabolism; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Down-Regulation; Gene Expression Regulation, Plant; Malates - metabolism; Mixed Function Oxygenases - biosynthesis; Mixed Function Oxygenases - genetics; Mixed Function Oxygenases - metabolism; MYB; phenylpropanoid; Phenylpropionates - metabolism; Plant Proteins - genetics; Plant Proteins - metabolism; Proto-Oncogene Proteins c-myb; Trans-Cinnamate 4-Monooxygenase; Transcription Factors - genetics; Transcription Factors - metabolism; Ultraviolet Rays; phenylpropanoid; Cell biology; UV; Plant Science; cinnamate 4-hydroxylase; MYB
• ISSN: 1360-1385; 1878-4372
• DOI: 10.1016/S1360-1385(01)01915-X

Mounting evidence indicates that members of the large family of plant MYB proteins are involved in the transcriptional regulation of an array of metabolic and developmental processes. Recently, the Arabidopsis thaliana MYB, AtMYB4, was shown to regulate the accumulation of the UV-protectant compound sinapoylmalate by repressing the transcription of the gene encoding the phenylpropanoid enzyme cinnamate 4-hydroxylase. AtMYB4 is thus a key regulator of phenylpropanoid pathway gene expression, and is the first example of a MYB protein that functions as a transcriptional repressor.