Anti-neuroinflammatory sesquiterpenoids from Chloranthus henryi

• Published in: Natural product research Vol. 37; no. 6; pp. 882 - 890
• Main Authors: Wang, Xue-Jiao, Xin, Jun-Li, Yu, Sheng-Zhou, Pan, Li-Long, Hu, Jin-Feng, Xiong, Juan
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 19.03.2023; Taylor & Francis Ltd
• Subjects: Animals; anti-neuroinflammation; Chloranthaceae; Chloranthus; Chloranthus henryi; Circular dichroism; circular dichroism spectroscopy; Dichroism; Dimers; Enantiomers; Inflammation; Lipopolysaccharides; Magnoliopsida - chemistry; Mice; Microglia; Molecular Structure; Nitric Oxide; Sesquiterpenes - chemistry; Sesquiterpenes - pharmacology; Sesquiterpenoids; Chloranthaceae; Chloranthus henryi; sesquiterpenoids; anti-neuroinflammation
• ISSN: 1478-6419; 1478-6427; 1478-6427
• DOI: 10.1080/14786419.2022.2095633

Hupelactones A (1) and B (2), two new eudesmanolide-type enantiomers of the corresponding compounds, along with four mono- (3-6) and nine dimeric- (7-15) known sesquiterpenoids were isolated from the whole plant of Chloranthus henryi var. hupehensis (syn. C. henryi). The new structures including the...