Acridone alkaloids and flavones from the leaves of Citrus reticulata

A new acridone alkaloid, reticarcidone A (1), decorated with an oxygenated isopentenyl group between C-1 and C-2, was isolated from the leaves of Citrus reticulata Blanco, together with nine known acridone alkaloids (2-10) and fifteen flavones compounds (11-25). The structure of those compounds were...

Full description

Saved in:
Bibliographic Details
Published inNatural product research Vol. 36; no. 14; pp. 3644 - 3650
Main Authors Ye, Ye, Xu, Gang, Li, Dong-Liang
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 15.07.2022
Taylor & Francis Ltd
Subjects
acridone alkaloids
Alkaloids
Citrus reticulata
cytotoxic activity
Cytotoxicity
Flavones
humans
neoplasm cells
NMR
Nuclear magnetic resonance
Toxicity
Tumor cell lines
Tumors
Two dimensional analysis
acridone alkaloids
flavones
cytotoxic activity
Citrus reticulata
Online AccessGet full text

Cover

More Information
Summary:A new acridone alkaloid, reticarcidone A (1), decorated with an oxygenated isopentenyl group between C-1 and C-2, was isolated from the leaves of Citrus reticulata Blanco, together with nine known acridone alkaloids (2-10) and fifteen flavones compounds (11-25). The structure of those compounds were confirmed by analysis of comprehensive 1D and 2D NMR, and MS data. Reticarcidone A (1) was the first pyrano[2,3-a]acridone isolated from the genus Citrus. Some of these compounds showed moderated cytotoxicity against the five human tumor cell lines MCF-7, SMMC-7721, HL-60, A549 and SW480.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1478-6419
1478-6427
1478-6427
DOI:10.1080/14786419.2021.1876047