BODIPY-containing nanoscale metal-organic frameworks for photodynamic therapy

BODIPY-immobilized zirconium-based nanoscale metal-organic frameworks (MOFs), named , have been synthesized through solvent-assisted ligand exchange using UiO-typed MOFs and pre-designed BODIPY ligands for the first time. The nanocrystal has been proved to possess good biocompatibility and highly ef...

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Published inChemical communications (Cambridge, England) Vol. 52; no. 31; pp. 5402 - 5405
Main Authors Wang, Weiqi, Wang, Lei, Li, Zhensheng, Xie, Zhigang
Format Journal Article
LanguageEnglish
Published England 01.01.2016
Subjects
Biocompatibility
Cancer
Exchange
Ligands
Metal-organic frameworks
Metalorganic compounds
Nanocrystals
Nanostructure
Photodynamic therapy
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Summary:BODIPY-immobilized zirconium-based nanoscale metal-organic frameworks (MOFs), named , have been synthesized through solvent-assisted ligand exchange using UiO-typed MOFs and pre-designed BODIPY ligands for the first time. The nanocrystal has been proved to possess good biocompatibility and highly efficient generation of singlet oxygen, which could kill the cancer cells effectively.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc01048b