Lues maligna in a chronic alcoholic patient

Lues maligna, which is characterized by noduloulcerative lesions, is a rare form of secondary syphilis. It is mainly seen in either HIV-infected or malnourished patients suffering from a depression in immunity. We presented a chronic alcoholic, HIV negative male patient with noduloulcerative lesions...

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Bibliographic Details
Published inJournal of dermatology Vol. 32; no. 3; p. 217
Main Authors Bayramgürler, Dilek, Bilen, Nilgün, Yildiz, Kürşat, Sikar, Aysun, Yavuz, Metin
Format Journal Article
LanguageEnglish
Published England 01.03.2005
Subjects
Adult
Alcoholism - complications
Alcoholism - immunology
Biopsy, Needle
Chronic Disease
Follow-Up Studies
Humans
Immunocompromised Host
Immunohistochemistry
Male
Penicillin G - therapeutic use
Risk Assessment
Severity of Illness Index
Syphilis Serodiagnosis
Syphilis, Cutaneous - complications
Syphilis, Cutaneous - drug therapy
Syphilis, Cutaneous - pathology
Treatment Outcome
Treponema pallidum - isolation & purification
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Summary:Lues maligna, which is characterized by noduloulcerative lesions, is a rare form of secondary syphilis. It is mainly seen in either HIV-infected or malnourished patients suffering from a depression in immunity. We presented a chronic alcoholic, HIV negative male patient with noduloulcerative lesions diagnosed as lues maligna based on his skin eruptions, results of serologic tests, and, histopathologic findings. We believe that chronic alcoholism could be the cause of immunosuppression in our case and wanted to emphasize the possibility of an association between lues maligna and chronic alcoholism.
ISSN:0385-2407
DOI:10.1111/j.1346-8138.2005.tb00749.x