Malignant melanoma and acquired dermal melanocytosis on congenital nevus spilus

We reported a case of malignant melanoma and acquired dermal melanocytosis that appeared on congenital nevus spilus; this is the first report from Japan. An 85-year-old woman had had a nevus spilus on the right lower leg since birth. A black-brown nodule developed on the nevus three years before tre...

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Bibliographic Details
Published inJournal of dermatology Vol. 32; no. 6; p. 454
Main Authors Yoneyama, Kei, Kamada, Noriaki, Mizoguchi, Masako, Utani, Atsushi, Kobayashi, Takashi, Shinkai, Hiroshi
Format Journal Article
LanguageEnglish
Published England 01.06.2005
Subjects
Aged
Aged, 80 and over
Biopsy, Needle
Cell Transformation, Neoplastic - pathology
Female
Follow-Up Studies
Humans
Immunohistochemistry
Lentigo - congenital
Lentigo - pathology
Lower Extremity
Melanocytes - pathology
Melanoma - pathology
Melanoma - surgery
Risk Assessment
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Treatment Outcome
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Summary:We reported a case of malignant melanoma and acquired dermal melanocytosis that appeared on congenital nevus spilus; this is the first report from Japan. An 85-year-old woman had had a nevus spilus on the right lower leg since birth. A black-brown nodule developed on the nevus three years before treatment. Blue-gray patches were found within the nevus on inspection. Histopathological analysis of these lesions revealed superficial spreading melanoma and acquired dermal melanocytosis, respectively. There have been 19 previous case reports of malignant melanoma on nevus spilus, and there have only been 4 cases of dermal melanocytosis (plaque-type blue nevus) on nevus spilus. We reviewed the reported cases in the literature and discussed the risk factors of nevus spilus.
ISSN:0385-2407
DOI:10.1111/j.1346-8138.2005.tb00779.x